Peter E. Fisher, MD, MBA

Our Pathologists and Scientists

Peter E. Fisher, MD, MBA

Peter E. Fisher, MD, MBA

President and CEO, Clinical Laboratory Director

Dr. Fisher is a graduate of the Middlesex Hospital Medical School, University of London. He completed his pathology residency and a postgraduate Fellowship in Advanced Pathology at the College of Physicians & Surgeons of Columbia University, New York. Dr. Fisher is a Diplomate of the American Board of Pathology and received his MBA from the Columbia Business School, NY, NY. Dr. Fisher’s clinical expertise includes cardiovascular, pulmonary, genitourinary, gastrointestinal and autopsy pathology. Dr. Fisher’s research focuses on cancer biology, cardiovascular disease and development, and he has authored more than 60 original research articles.

Publications:

Prediction of breast cancer using volatile biomarkers in the breath.
Phillips M, Cataneo RN, Ditkoff BA, Fisher P, Greenberg J, Gunawardena R, Kwon CS, Tietje O, Wong C.
Breast Cancer Res Treat. 2006 Sep;99(1):19-21. Epub 2006 Feb 24.PMID: 16502014

Prediction of heart transplant rejection with a breath test for markers of oxidative stress.
Phillips M, Boehmer JP, Cataneo RN, Cheema T, Eisen HJ, Fallon JT, Fisher PE, Gass A, Greenberg J, Kobashigawa J, Mancini D, Rayburn B, Zucker MJ.
Am J Cardiol. 2004 Dec 15;94(12):1593-4.PMID: 15589029

Heart allograft rejection: detection with breath alkanes in low levels (the HARDBALL study).
Phillips M, Boehmer JP, Cataneo RN, Cheema T, Eisen HJ, Fallon JT, Fisher PE, Gass A, Greenberg J, Kobashigawa J, Mancini D, Rayburn B, Zucker MJ.
J Heart Lung Transplant. 2004 Jun;23(6):701-8.PMID: 15366430

Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
Kiaris H, Politi K, Grimm LM, Szabolcs M, Fisher P, Efstratiadis A, Artavanis-Tsakonas S.
Am J Pathol. 2004 Aug;165(2):695-705.PMID: 15277242 Free PMC Article

'Designer' tumors in mice.
Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A.
2004 Feb 26;23(8):1558-65.PMID: 14661057

Essential role for ADAM19 in cardiovascular morphogenesis.
Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP.
Mol Cell Biol. 2004 Jan;24(1):96-104.PMID: 14673146 Free PMC Article

A mouse model of uterine leiomyosarcoma.
Politi K, Szabolcs M, Fisher P, Kljuic A, Ludwig T, Efstratiadis A.
Am J Pathol. 2004 Jan;164(1):325-36.PMID: 14695345 Free PMC Article

The ShiA protein encoded by the Shigella flexneri SHI-2 pathogenicity island attenuates inflammation.
Ingersoll MA, Moss JE, Weinrauch Y, Fisher PE, Groisman EA, Zychlinsky A.
Cell Microbiol. 2003 Nov;5(11):797-807.PMID: 14531895

Volatile markers of breast cancer in the breath.
Phillips M, Cataneo RN, Ditkoff BA, Fisher P, Greenberg J, Gunawardena R, Kwon CS, Rahbari-Oskoui F, Wong C.
Breast J. 2003 May-Jun;9(3):184-91. Erratum in: Breast J. 2003 Jul-Aug;9(4):345.PMID: 12752626

Assessment of myocardial recovery in a patient with acute myocarditis supported with a left ventricular assist device: a case report.
Maybaum S, Stockwell P, Naka Y, Catanese K, Flannery M, Fisher P, Oz M, Mancini D.
J Heart Lung Transplant. 2003 Feb;22(2):202-9.PMID: 12581771

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.
Xuan S, Kitamura T, Nakae J, Politi K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A.
J Clin Invest. 2002 Oct;110(7):1011-9.PMID: 12370279 Free PMC Article

Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice.
Chua S Jr, Liu SM, Li Q, Yang L, Thassanapaff VT, Fisher P.
2002 Jul;45(7):976-90. Epub 2002 Jun 6.PMID: 12136396


Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling.
Chiao E, Fisher P, Crisponi L, Deiana M, Dragatsis I, Schlessinger D, Pilia G, Efstratiadis A.
Dev Biol. 2002 Mar 1;243(1):185-206.PMID: 11846487

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice.
Podsypanina K, Lee RT, Politis C, Hennessy I, Crane A, Puc J, Neshat M, Wang H, Yang L, Gibbons J, Frost P, Dreisbach V, Blenis J, Gaciong Z, Fisher P, Sawyers C, Hedrick-Ellenson L, Parsons R.
Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10320-5. Epub 2001 Aug 14.PMID: 11504907 Free PMC Article

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice.
Ludwig T, Fisher P, Murty V, Efstratiadis A. 2001 Jul 5;20(30):3937-48.PMID: 11494122 Free Article

Painful myopathy and end-stage renal disease.
Kunis CL, Markowitz GS, Liu-Jarin X, Fisher PE, Frei GL, D'Agati VD.
Am J Kidney Dis. 2001 May;37(5):1098-104. No abstract available.PMID: 11325695

Tumorigenesis in mice carrying a truncating Brca1 mutation.
Ludwig T, Fisher P, Ganesan S, Efstratiadis A.
Genes Dev. 2001 May 15;15(10):1188-93.PMID: 11358863 Free PMC Article


Indirect allorecognition in heart allograft rejection.
Ciubotariu R, Liu Z, Ho E, Vasilescu R, Foca-Rodi A, Colovai AI, Fisher P, Hardy M, Rose EA, Cortesini R, Suciu Foca Cortesini N.
Transplant Proc. 2001 Feb-Mar;33(1-2):1612. No abstract available.PMID: 11267441


The regulatory protein PhoP controls susceptibility to the host inflammatory response in Shigella flexneri.
Moss JE, Fisher PE, Vick B, Groisman EA, Zychlinsky A.Cell Microbiol. 2000 Dec;2(6):443-52.PMID: 11207599

Improvement of rejection-induced diastolic abnormalities in rat cardiac allografts with inducible nitric oxide synthase inhibition.
Soto PF, Jia CX, Rabkin DG, Hart JP, Carter YM, Sardo MJ, Hsu DT, Fisher PE, Pinsky DJ, Spotnitz HM.
J Thorac Cardiovasc Surg. 2000 Jul;120(1):39-46.PMID: 10884653



Coronary perfusate composition influences diastolic properties, myocardial water content, and histologic characteristics of the rat left ventricle.
Starr JP, Jia CX, Amirhamzeh MM, Rabkin DG, Hart JP, Hsu DT, Fisher PE, Szabolcs M, Spotnitz HM.
Ann Thorac Surg. 1999 Sep;68(3):925-30.PMID: 10509985


Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems.
Podsypanina K, Ellenson LH, Nemes A, Gu J, Tamura M, Yamada KM, Cordon-Cardo C, Catoretti G, Fisher PE, Parsons R.
Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1563-8.PMID: 9990064 Free PMC Article

Effect of improved myocardial protection on edema and diastolic properties of the rat left ventricle during acute allograft rejection.
Soto PF, Jia CX, Carter YM, Rabkin D, Starr JP, Amirhamzeh MM, Hsu DT, Sciacca R, Fisher PE, Spotnitz HM.
J Heart Lung Transplant. 1998 Jun;17(6):608-16.PMID: 9662097

Intraabdominal immunoglobulin light chain amyloid tumor encompassing a vascular malformation.
Tsang P, Fisher PE.
Am J Hematol. 1998 Jun;58(2):154-5. No abstract available.PMID: 9625589

Evidence of vascular growth associated with laser treatment of normal canine myocardium.
Fisher PE, Kohmoto T, DeRosa CM, Yamamoto N,Failey P, Smith CR, Burkhoff D.
Ann Thorac Surg. 1998 May;65(5):1360-7.PMID: 9594867


Diastolic properties, myocardial water content, and histologic condition of the rat left ventricle: effect of varied osmolarity of a coronary perfusate.
Carter YM, Jia CX, Soto PF, Starr JP, Rabkin DG, Hsu DT, Fisher PE, Spotnitz HM.
J Heart Lung Transplant. 1998 Feb;17(2):140-9.PMID: 9513852

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes.
Eggenschwiler J, Ludwig T, Fisher P, Leighton PA, Tilghman SM, Efstratiadis A.
Genes Dev. 1997 Dec 1;11(23):3128-42.PMID: 9389646 Free PMC Article

New strategies for early diagnosis of heart allograft rejection.
Tugulea S, Ciubotariu R, Colovai AI, Liu Z, Itescu S, Schulman LL, Fisher PE, Hardy MA, Rose EA, Michler RE, Cortesini R, Suciu-Foca N.
Transplantation. 1997 Sep 27;64(6):842-7.PMID: 9326408

Histologic analysis of transmyocardial channels: comparison of CO2 and holmium:YAG lasers.
Fisher PE, Khomoto T, DeRosa CM, Spotnitz HM, Smith CR, Burkhoff D.
Ann Thorac Surg. 1997 Aug;64(2):466-72.PMID: 9262595


Indirect T-cell recognition in human allograft rejection.
Suciu-Foca N, Liu Z, Colovai AI, Fisher P, Ho E, Reed EF, Rose EA, Michler RE, Hardy MA, Cocciolo P, Gargano F, Cortesini R.
Transplant Proc. 1997 Feb-Mar;29(1-2 /01):1012-3. No abstract available.PMID: 9123174


Characterizing ventricular mechanics and energetics following repeated coronary microembolization.
Todaka K, Leibowitz D, Homma S, Fisher PE, Derosa C, Stennett R, Packer M, Burkhoff D.
Am J Physiol. 1997 Jan;272(1 Pt 2):H186-94.PMID: 9038937

Physiology, histology, and 2-week morphology of acute transmyocardial channels made with a CO2 laser.
Kohmoto T, Fisher PE, Gu A, Zhu SM, DeRosa CM, Smith CR, Burkhoff D.
Ann Thorac Surg. 1997 May;63(5):1275-83.PMID: 9146314


Assessment of transmyocardial perfusion in alligator hearts.
Kohmoto T, Argenziano M, Yamamoto N, Vliet KA, Gu A, DeRosa CM, Fisher PE, Spotnitz HM, Burkhoff D, Smith CR.
Circulation. 1997 Mar 18;95(6):1585-91.PMID: 9118529 Free Article

Physiology, histology, and 2-week morphology of acute transmyocardial channels made with a CO2 laser.
Kohmoto T, Fisher PE, Gu A, Zhu SM, DeRosa CM, Smith CR, Burkhoff D.
Ann Thorac Surg. 1997 May;63(5):1275-83.PMID: 9146314

Indirect recognition of donor HLA-DR peptides in organ allograft rejection.
Liu Z, Colovai AI, Tugulea S, Reed EF, Fisher PE, Mancini D, Rose EA, Cortesini R, Michler RE, Suciu-Foca N.
J Clin Invest. 1996 Sep 1;98(5):1150-7.PMID: 8787678 Free PMC Article

Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family.
Su ZZ, Lin J, Shen R, Fisher PE, Goldstein NI, Fisher PB.
Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7252-7.PMID: 8692978 Free PMC Article

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds.
Ludwig T, Eggenschwiler J, Fisher P, D'Ercole AJ, Davenport ML, Efstratiadis A.
Dev Biol. 1996 Aug 1;177(2):517-35.PMID: 8806828

Consistencies and controversies in the application of the International Society for Heart and Lung Transplantation working formulation for heart transplant biopsy specimens. Rapamycin Cardiac Rejection Treatment Trial Pathologists.
Winters GL, McManus BM.
J Heart Lung Transplant. 1996 Jul;15(7):728-35.PMID: 8820790

Histologic appearance of transmyocardial laser channels after 4 1/2 weeks.
Burkhoff D, Fisher PE, Apfelbaum M, Kohmoto T, DeRosa CM, Smith CR.
Ann Thorac Surg. 1996 May;61(5):1532-4; discussion 1534-5.PMID: 8633979

Does blood flow through holmium:YAG transmyocardial laser channels?
Kohmoto T, Fisher PE, Gu A, Zhu SM, Yano OJ, Spotnitz HM, Smith CR, Burkhoff D.
Ann Thorac Surg. 1996 Mar;61(3):861-8.PMID: 8619707

Additive value of immunologic monitoring to histologic grading of heart allograft biopsy specimens: implications for therapy.
Fisher PE, Suciu-Foca N, Ho E, Michler RE, Rose EA, Mancini D.
J Heart Lung Transplant. 1995 Nov-Dec;14(6 Pt 1):1156-61.PMID: 8719463

Experience with heart transplantation for cardiac tumors.
Goldstein DJ, Oz MC, Rose EA, Fisher P, Michler RE.
J Heart Lung Transplant. 1995 Mar-Apr;14(2):382-6.PMID: 7779860

LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells.
Xu Y, Baldassare M, Fisher P, Rathbun G, Oltz EM, Yancopoulos GD, Jessell TM, Alt FW.
Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):227-31.PMID: 7678338 Free PMC Article

Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.
Charron J, Malynn BA, Fisher P, Stewart V, Jeannotte L, Goff SP, Robertson EJ, Alt FW.
Genes Dev. 1992 Dec;6(12A):2248-57.PMID: 1459450 Free Article

A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system.
Collum RG, Fisher PE, Datta M, Mellis S, Thiele C, Huebner K, Croce CM, Israel MA, Theil T, Moroy T, et al.
Nucleic Acids Res. 1992 Sep 25;20(18):4919-25.PMID: 1357630 Free PMC Article

Surface IgM mediated regulation of RAG gene expression in E mu-N-myc B cell lines.
Ma A, Fisher P, Dildrop R, Oltz E, Rathbun G, Achacoso P, Stall A, Alt FW.
Alt FW.EMBO J. 1992 Jul;11(7):2727-34.PMID: 1628630 Free PMC Article

High frequency of myelomonocytic tumors in aging E mu L-myc transgenic mice.
Möröy T, Fisher PE, Lee G, Achacoso P, Wiener F, Alt FW.
J Exp Med. 1992 Feb 1;175(2):313-22.PMID: 1310099 Free PMC Article


IgH enhancer deregulated expression of L-myc: abnormal T lymphocyte development and T cell lymphomagenesis.
Möröy T, Fisher P, Guidos C, Ma A, Zimmerman K, Tesfaye A, DePinho R, Weissman I, Alt FW.
EMBO J. 1990 Nov;9(11):3659-66.PMID: 2120050

Fine needle aspiration biopsy of intramammary neurilemoma.
Fisher PE, Estabrook A, Cohen MB.
Acta Cytol. 1990 Jan-Feb;34(1):35-7.PMID: 2296838

Fine needle aspiration biopsy diagnosis of mucoepidermoid carcinoma. Statistical analysis.
Fisher PE, Cohen MB,Holly EA, Ljung BM, Löwhagen T, Bottles K.
Acta Cytol. 1990 Jan-Feb;34(1):43-9.PMID: 2296840

Hypopharyngeal mesenchymomas.
Gordon LJ, Wazen JJ, Fisher P, Perzi KH.
Otolaryngol Head Neck Surg. 1990 Jul;103(1):124-7. Review. No abstract available.PMID: 2117721

Ergotamine abuse and extra-hepatic portal hypertension.
Fisher PE, Silk DB, Menzies-Gow N, Dingle M.
Postgrad Med J. 1985 May;61(715):461-3.PMID: 4022885

Differences in alignment of normal and transformed cells on glass fibres.
Tickle C., Fisher PE.
Exp Cell Res. 1981 Feb;131(2):407-10. No abstract available.PMID: 7202540

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